September 21, 2023
Re-analysing Ebola spread in Sierra Leone: The importance of local social dynamics

Re-analysing Ebola spread in Sierra Leone: The importance of local social dynamics

Background: The 2013-15 Ebola epidemic in West Africa was the biggest up to now recorded, and primarily affected three adjoining nations, Guinea, Liberia and Sierra Leone. The worst affected nation (by way of confirmed circumstances) was Sierra Leone. The current paper seems to be on the epidemic in Sierra Leone. The epidemic on this nation was a concatenation of native outbreaks. These native outbreaks are usually not properly characterised by evaluation utilizing commonplace numerical methods. Partly, this displays difficulties in file assortment on the peak of the epidemic. This paper presents a unique method, based mostly on utility of field-based methods of social investigation that present a richer understanding of the epidemic.
Strategies: In a post-epidemic research (2016-18) of two districts (Bo and Moyamba) we use ethnographic information to reconstruct native an infection pathways from proof offered by affected communities, cross-referenced to information of the epidemic retained by the Nationwide Ebola Response Fee, now lodged within the Ebola Museum and Archive at Njala College. Our research paperwork and discusses native social and contextual elements largely lacking from beforehand revealed research.
Outcomes: Our main discovering is that the epidemic in Sierra Leone was a collection of native outbreaks, a few of which had been higher contained than others. In people who weren’t properly contained, various contingent elements helps clarify lack of management. A number of numerical research have drawn consideration to the significance of native heterogeneities within the Sierra Leone Ebola epidemic. Our qualitative research throws particular mild on various components that designate these heterogeneities: the position of externalities, well being system deficiencies, cultural concerns and native coping capacities.
Conclusions: Social points and native contingencies clarify the unfold of Ebola in Sierra Leone and are key to understanding heterogeneities in epidemiological information. Integrating ethnographic analysis into epidemic-response is crucial to correctly perceive the patterns of unfold and the alternatives to intervene. This conclusion has vital implications for future interdisciplinary analysis and interpretation of ordinary numerical information, and consequently for management of epidemic outbreaks.

Analysis of novel HIV vaccine candidates utilizing recombinant vesicular stomatitis virus vector produced in serum-free Vero cell cultures

Acquired Immune Deficiency Syndrome (AIDS) in people is a results of the destruction of the immune system attributable to Human Immunodeficiency Virus (HIV) an infection. This critical epidemic continues to be progressing world-wide. Regardless of advances in therapy, a protected and efficient preventive HIV vaccine is desired to fight this illness, and to save lots of hundreds of thousands of lives. Nonetheless, such a vaccine shouldn’t be accessible but though in depth quantities of assets in analysis and improvement have been invested over three a long time. In mild of the not too long ago accepted Ebola virus illness vaccine based mostly on a recombinant vesicular stomatitis virus (rVSV-ZEBOV), we current the outcomes of our work on three novel VSV-vectored HIV vaccine candidates. We describe the design, rescue, manufacturing and purification methodology and consider their immunogenicity in mice previous to preclinical research that will likely be carried out in non-human primates.
The manufacturing of every of the three candidate vaccines (rVSV-B6-NL4.3Env/SIVtm, rVSV-B6-NL4.3Env/Ebtm and rVSV-B6-A74Env(PN6)/SIVtm) was evaluated in small scale in Vero cells and it was discovered that manufacturing kinetics on Vero cells differ relying on the HIV gp floor protein used. Purified virus preparations complied with the WHO restrictions for the residual DNA and host cell protein contents. Lastly, when administered to mice, all three rVSV-HIV vaccine candidates induced an HIV gp140-specific antibody response. Greater than 423349 deaths had occurred globally and continues to be growing each day. The entire world is beneath a well being emergency, and individuals are suggested to remain at their houses to keep away from the unfold of person-to-person an infection, and suggested to keep up social distancing.
The development in medical analysis methods like Actual-Time PCR (RT-PCR), immunological, microscopy, and geographic data system (GIS) mapping expertise helped in tacking the fast analysis and monitoring viral an infection in a brief interval. In the identical means, synthetic intelligence (AI), combinatorial chemistry, and deep studying approaches assist to search out novel therapeutics in much less time and extensive applicability in biomedical analysis. Nationwide Institute of Allergy and Infectious Illnesses (NIAID) has began the medical trials of investigation COVID-19 vaccine. Due to this fact, we will anticipate vaccines to be accessible for this lethal illness within the coming few months.
Re-analysing Ebola spread in Sierra Leone: The importance of local social dynamics
Re-analysing Ebola spread in Sierra Leone: The importance of local social dynamics

Screening for Anti-Influenza Actives of Prefractionated Conventional Chinese language Medicines

Moreover, all of the ten hit fractions inhibited the propagation of progeny influenza virus considerably at 20 μg/mL. The hit TCM fractions deserve additional isolation for accountable constituents main in the direction of anti-influenza medication. Furthermore, a library consisting of 500 simplified TCM extracts was established, facilitating antiviral screening in fast response to rising and re-emerging viruses reminiscent of Ebola virus and present SARS-CoV-2 pandemic. Phosphatidylserine (PS) receptors mediate clearance of apoptotic cells-efferocytosis-by recognizing the PS uncovered on these cells. Additionally they mediate the entry of enveloped viruses by binding PS within the virion membrane. Right here we present that phosphatidylethanolamine (PE) synergizes with PS to boost PS receptor-mediated efferocytosis and virus entry.

Infectious salmon anemia virus PCR kit

PCR-V260-96R 100T
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Infectious bursal disease virus PCR kit

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Infectious bursal disease virus PCR kit

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Yellow fever virus infectious culture fluid(17D)

DAGF-040 1ml
EUR 774

Equine infectious anemia virus RT PCR kit

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Equine infectious anemia virus RT PCR kit

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Infectious salmon anemia virus RT PCR kit

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Infectious bursal disease virus RT PCR kit

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Infectious bursal disease virus RT PCR kit

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EUR 2144.4

Infectious bursal disease virus RT PCR kit

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EUR 1155.6

Avian infectious bronchitis virus PCR kit

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EUR 987.6

Avian infectious bronchitis virus PCR kit

PCR-V051-96R 100T
EUR 1335.6

Infectious Laryngotracheitis virus PCR kit

PCR-V009-48D 50T
EUR 543.6

Infectious Laryngotracheitis virus PCR kit

PCR-V009-96D 100T
EUR 686.4

Avian infectious bronchitis virus RT PCR kit

RTq-V051-100R 100T
EUR 1573.2

Avian infectious bronchitis virus RT PCR kit

RTq-V051-150R 150T
EUR 2144.4

Avian infectious bronchitis virus RT PCR kit

RTq-V051-50R 50T
EUR 1155.6

Infectious pancreatic necrosis virus PCR kit

PCR-V259-48R 50T
EUR 987.6

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PCR-V259-96R 100T
EUR 1335.6

Infectious Laryngotracheitis virus RT PCR kit

RTq-V009-100D 100T
EUR 860.4

Infectious Laryngotracheitis virus RT PCR kit

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Infectious Laryngotracheitis virus RT PCR kit

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Infectious pancreatic necrosis virus RT PCR kit

RTq-V259-100R 100T
EUR 1573.2

Infectious pancreatic necrosis virus RT PCR kit

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EUR 2144.4

Infectious pancreatic necrosis virus RT PCR kit

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EUR 1155.6

Infectious salmon anemia virus One-Step PCR kit

Oneq-V260-100R 100T
EUR 1932

Infectious salmon anemia virus One-Step PCR kit

Oneq-V260-150R 150T
EUR 2646

Infectious salmon anemia virus One-Step PCR kit

Oneq-V260-50R 50T
EUR 1410

Equine infectious anemia virus One-Step PCR kit

Oneq-V162-100R 100T
EUR 1932

Equine infectious anemia virus One-Step PCR kit

Oneq-V162-150R 150T
EUR 2646

Equine infectious anemia virus One-Step PCR kit

Oneq-V162-50R 50T
EUR 1410

Infectious hematopoietic necrosis virus PCR kit

PCR-V265-48R 50T
EUR 987.6

Infectious hematopoietic necrosis virus PCR kit

PCR-V265-96R 100T
EUR 1335.6

Infectious bursal disease virus One-Step PCR kit

Oneq-V052-100R 100T
EUR 1932

Infectious bursal disease virus One-Step PCR kit

Oneq-V052-150R 150T
EUR 2646

Infectious bursal disease virus One-Step PCR kit

Oneq-V052-50R 50T
EUR 1410

Chicken Infectious Bronchitis Virus (IBV) ELISA Kit

abx055758-96tests 96 tests
EUR 801.6

Infectious hematopoietic necrosis virus RT PCR kit

RTq-V265-100R 100T
EUR 1573.2

Infectious hematopoietic necrosis virus RT PCR kit

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EUR 2144.4

Infectious hematopoietic necrosis virus RT PCR kit

RTq-V265-50R 50T
EUR 1155.6

Avian infectious bronchitis virus One-Step PCR kit

Oneq-V051-100R 100T
EUR 1932

Avian infectious bronchitis virus One-Step PCR kit

Oneq-V051-150R 150T
EUR 2646

Avian infectious bronchitis virus One-Step PCR kit

Oneq-V051-50R 50T
EUR 1410

Native Feline Infectious Peritonitis Virus antigen

DAGA-3038 1mg
EUR 1248

Penaeid shrimp infectious myonecrosis virus PCR kit

PCR-V290-48R 50T
EUR 987.6

Penaeid shrimp infectious myonecrosis virus PCR kit

PCR-V290-96R 100T
EUR 1335.6

Avian infectious bronchitis virus Q1 genotype PCR kit

PCR-V506-48R 50T
EUR 987.6

Avian infectious bronchitis virus Q1 genotype PCR kit

PCR-V506-96R 100T
EUR 1335.6

Chicken Infectious Bursal Disease Virus (IBDV) ELISA Kit

abx050271-96tests 96 tests
EUR 801.6

Penaeid shrimp infectious myonecrosis virus RT PCR kit

RTq-V290-100R 100T
EUR 1573.2

Penaeid shrimp infectious myonecrosis virus RT PCR kit

RTq-V290-150R 150T
EUR 2144.4

Penaeid shrimp infectious myonecrosis virus RT PCR kit

RTq-V290-50R 50T
EUR 1155.6

Infectious bursal disease virus Pathotyping RT PCR kit

RTq-V589-100R 100T
EUR 1573.2

Infectious bursal disease virus Pathotyping RT PCR kit

RTq-V589-150R 150T
EUR 2144.4

Infectious bursal disease virus Pathotyping RT PCR kit

RTq-V589-50R 50T
EUR 1155.6

Infectious Laryngotracheitis virus One-Step PCR kit

Oneq-V009-100D 100T
EUR 1039.2

Infectious Laryngotracheitis virus One-Step PCR kit

Oneq-V009-150D 150T
EUR 1177.2

Infectious Laryngotracheitis virus One-Step PCR kit

Oneq-V009-50D 50T
EUR 861.6

Avian infectious bronchitis virus Q1 genotype RT PCR kit

RTq-V506-100R 100T
EUR 1573.2

Avian infectious bronchitis virus Q1 genotype RT PCR kit

RTq-V506-150R 150T
EUR 2144.4

Avian infectious bronchitis virus Q1 genotype RT PCR kit

RTq-V506-50R 50T
EUR 1155.6

Infectious pancreatic necrosis virus One-Step PCR kit

Oneq-V259-100R 100T
EUR 1932

Infectious pancreatic necrosis virus One-Step PCR kit

Oneq-V259-150R 150T
EUR 2646

Infectious pancreatic necrosis virus One-Step PCR kit

Oneq-V259-50R 50T
EUR 1410

Chicken Infectious Bronchitis Virus Antibody ELISA Kit

abx364912-96tests 96 tests
EUR 764.4

Infectious hematopoietic necrosis virus One-Step PCR kit

Oneq-V265-100R 100T
EUR 1932

Infectious hematopoietic necrosis virus One-Step PCR kit

Oneq-V265-150R 150T
EUR 2646

Infectious hematopoietic necrosis virus One-Step PCR kit

Oneq-V265-50R 50T
EUR 1410

Avian infectious bronchitis virus Variant Israiel 02 PCR kit

PCR-V070-48R 50T
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Avian infectious bronchitis virus Variant Israiel 02 PCR kit

PCR-V070-96R 100T
EUR 1335.6

Infectious bronchitis virus Spike glycoprotein S1 subunit (S1)

1-CSB-RP182154v
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Infectious bronchitis virus Spike glycoprotein S1 subunit(S1),partial expressed in E.coli

Avian infectious bronchitis virus Variant Israiel 02 RT PCR kit

RTq-V070-100R 100T
EUR 1573.2

Avian infectious bronchitis virus Variant Israiel 02 RT PCR kit

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Avian infectious bronchitis virus Variant Israiel 02 RT PCR kit

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Penaeid shrimp infectious myonecrosis virus One-Step PCR kit

Oneq-V290-100R 100T
EUR 1932

Penaeid shrimp infectious myonecrosis virus One-Step PCR kit

Oneq-V290-150R 150T
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Penaeid shrimp infectious myonecrosis virus One-Step PCR kit

Oneq-V290-50R 50T
EUR 1410

Infectious bursal disease virus Pathotyping One-Step PCR kit

Oneq-V589-100R 100T
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Infectious bursal disease virus Pathotyping One-Step PCR kit

Oneq-V589-150R 150T
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Infectious bursal disease virus Pathotyping One-Step PCR kit

Oneq-V589-50R 50T
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Avian infectious bursal disease virus Structural polyprotein

1-CSB-RP182094V
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Avian infectious bursal disease virus Structural polyprotein,partial expressed in E.coli

Avian infectious bronchitis virus Vatiant Masschusett PCR kit

PCR-V069-48R 50T
EUR 987.6

Avian infectious bronchitis virus Vatiant Masschusett PCR kit

PCR-V069-96R 100T
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Avian infectious bronchitis virus Q1 genotype One-Step PCR kit

Oneq-V506-100R 100T
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Avian infectious bronchitis virus Q1 genotype One-Step PCR kit

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Avian infectious bronchitis virus Q1 genotype One-Step PCR kit

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Infectious hypodermal and hematopoietic necrosis virus PCR kit

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Infectious hypodermal and hematopoietic necrosis virus PCR kit

PCR-V279-96D 100T
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Avian infectious bronchitis virus Vatiant Masschusett RT PCR kit

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Avian infectious bronchitis virus Vatiant Masschusett RT PCR kit

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Avian infectious bronchitis virus Vatiant Masschusett RT PCR kit

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Infectious hypodermal and hematopoietic necrosis virus RT PCR kit

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Infectious hypodermal and hematopoietic necrosis virus RT PCR kit

RTq-V279-150D 150T
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Infectious hypodermal and hematopoietic necrosis virus RT PCR kit

RTq-V279-50D 50T
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Avian infectious bronchitis virus Variant Israiel 02 One-Step PCR kit

Oneq-V070-100R 100T
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Avian infectious bronchitis virus Variant Israiel 02 One-Step PCR kit

Oneq-V070-150R 150T
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Avian infectious bronchitis virus Variant Israiel 02 One-Step PCR kit

Oneq-V070-50R 50T
EUR 1410

Avian infectious bronchitis virus Vatiant Masschusett One-Step PCR kit

Oneq-V069-100R 100T
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Avian infectious bronchitis virus Vatiant Masschusett One-Step PCR kit

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Avian infectious bronchitis virus Vatiant Masschusett One-Step PCR kit

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Infectious hypodermal and hematopoietic necrosis virus One-Step PCR kit

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Infectious hypodermal and hematopoietic necrosis virus One-Step PCR kit

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Infectious hypodermal and hematopoietic necrosis virus One-Step PCR kit

Oneq-V279-50D 50T
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Human immunodeficiency virus type 1 group M subtype B Virion infectivity factor (vif)

1-CSB-YP303185HKM
  • EUR 814.80
  • EUR 402.00
  • EUR 2606.40
  • EUR 1261.20
  • EUR 1730.40
  • EUR 522.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human immunodeficiency virus type 1 group M subtype B Virion infectivity factor(vif) expressed in Yeast

HIV Infection Enhancer (Medium) (1 ml)

H901-1 - Ask for price

HIV Infection Enhancer (Medium) (200 µl)

H901-02 - Ask for price

Parasite infection tissue array

BIC49001 each
EUR 198
Description: Parasite infection tissue array, 12cases/ 24cores

Hexamethrine Bromide for viral infection enhancement (10 mg/ml in sterile water)

ABP-SC-HEXBR01 1 ml Ask for price

Hexamethrine Bromide for viral infection enhancement (10 mg/ml in sterile water)

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Mononucleosis Infection Antigen Protein

abx169706-1mg 1 mg
EUR 343.2

Liver cancer tissue array with HBV infection information

LV1003 each
EUR 306
Description: Liver cancer tissue array with HBV infection information, including pathology grade, TNM and clinical stage, 50 cases/100 cores

Modulator of Retrovirus Infection Homolog (MRI) Antibody

20-abx313941
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Mouse Modulator of retrovirus infection homolog, Mri ELISA KIT

ELI-12956m 96 Tests
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Human Modulator of retrovirus infection homolog, MRI ELISA KIT

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EUR 988.8

Recombinant FeLV Infection accessory factor (aa 33-273) [His] Protein

VAng-Wyb2971-100gEcoli 100 µg (E. coli)
EUR 4002
Description: Feline leukemia virus Infection accessory factor protein, recombinant protein.

Recombinant FeLV Infection accessory factor (aa 33-273) [His] Protein

VAng-Wyb2971-500gEcoli 500 µg (E. coli)
EUR 9794.4
Description: Feline leukemia virus Infection accessory factor protein, recombinant protein.

vaccinia virus?infected A549 cells (TV08) , DNA Aptamer, unlabeled

AD-153-U Custom Ask for price

vaccinia virus?infected A549 cells (TV08) , DNA Aptamer, FITC labeled

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vaccinia virus?infected A549 cells (TV08) , DNA Aptamer, Biotinylated

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QPCR Kit RNA Infectious

MOL8780 EACH
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QPCR Kit RNA Infectious

MOL8788 EACH
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QPCR Kit RNA Infectious Mmix

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QPCR Kit RNA Infectious Mmix

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25L infectious waste card bin

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Chicken Infectious Coryza ELISA Kit

abx052624-96tests 96 tests
EUR 801.6

Chicken infectious coryza,ic ELISA Kit

CN-00804C1 96T
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Chicken infectious coryza,ic ELISA Kit

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EUR 349.2

Chicken infectious coryza ELISA Kit

ELA-E0989d 96 Tests
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Chicken infectious coryza, IC ELISAKit

QY-E80051 96T
EUR 511.2

Pig Infectious mononucleosis IgG ELISA kit

E07I0001-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Porcine Infectious mononucleosis IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Infectious mononucleosis IgG ELISA kit

E07I0001-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Porcine Infectious mononucleosis IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Infectious mononucleosis IgG ELISA kit

E07I0001-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine Infectious mononucleosis IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Infectious mononucleosis IgI ELISA kit

E07I0002-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Porcine Infectious mononucleosis IgI in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Infectious mononucleosis IgI ELISA kit

E07I0002-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Porcine Infectious mononucleosis IgI in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Infectious mononucleosis IgI ELISA kit

E07I0002-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine Infectious mononucleosis IgI in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Infectious mononucleosis IgG ELISA kit

E08I0001-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Canine Infectious mononucleosis IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
The presence of PE on the identical floor as PS dramatically enhances recognition of PS by PS-binding proteins reminiscent of GAS6, PROS, and TIM1. Liposomes containing each PE and PS certain to GAS6 and had been engulfed by AXL-expressing cells way more effectively than these containing PS alone. Additional, an infection of AXL-expressing cells by infectious Zika virus or Ebola, Chikungunya or japanese equine encephalitis pseudoviruses was inhibited with better effectivity by the liposomes containing each PS and PE in comparison with a mix of liposomes individually composed of PS and PE.

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