The only-injection vaccine protects nonhuman primates towards an infection with marburg virus and three species of ebola virus. The filoviruses Marburg virus and Ebola virus trigger extreme hemorrhagic fever with excessive mortality in people and nonhuman primates. Among the many most promising filovirus vaccines below improvement is a system primarily based on recombinant vesicular stomatitis virus (VSV) that expresses a single filovirus glycoprotein (GP) rather than the VSV glycoprotein (G).
Right here, we carried out a proof-of-concept examine as a way to decide the potential of getting one single-injection vaccine able to defending nonhuman primates towards Sudan ebolavirus (SEBOV), Zaire ebolavirus (ZEBOV), Cote d’Ivoire ebolavirus (CIEBOV), and Marburgvirus (MARV). On this examine, 11 cynomolgus monkeys had been vaccinated with a blended vaccine consisting of equal elements of the vaccine vectors VSVDeltaG/SEBOVGP, VSVDeltaG/ZEBOVGP, and VSVDeltaG/MARVGP.
4 weeks later, three of those animals had been challenged with MARV, three with CIEBOV, three with ZEBOV, and two with SEBOV. Three management animals had been vaccinated with VSV vectors encoding a nonfilovirus GP and challenged with SEBOV, ZEBOV, and MARV, respectively, and 5 unvaccinated management animals had been challenged with CIEBOV . Importantly, not one of the macaques vaccinated with the blended vaccine succumbed to a filovirus problem.
As anticipated, an experimental management animal vaccinated with VSVDeltaG/ZEBOVGP and challenged with SEBOV succumbed, as did the constructive controls challenged with SEBOV, ZEBOV, and MARV, respectively. All 5 management animals challenged with CIEBOV turned severely in poor health, and three of the animals succumbed on days 12, 12, and 14, respectively.
The 2 animals that survived CIEBOV an infection had been shielded from subsequent problem with both SEBOV or ZEBOV, suggesting that immunity to CIEBOV could also be protecting towards different species of Ebola virus . In conclusion, we developed an immunization scheme primarily based on a single-injection vaccine that protects nonhuman primates towards deadly problem with consultant strains of all human pathogenic filovirus species.
zebov-detection
OPCA05225-100UG - Nucleoprotein Recombinant Protein (Zaire Ebola virus)
OPCA05225-100UG
Aviva Systems Biology
100ug
EUR 668
OPCA05225-500UG - Nucleoprotein Recombinant Protein (Zaire Ebola virus)
OPCA05225-500UG
Aviva Systems Biology
500ug
EUR 1534
Mouse Anti-Zaire Ebola virus Nucleoprotein (NP) IgG ELISA Kit, 96 tests, Quantitative
AE-320500-1
Alpha Diagnostics
1 Kit
EUR 1074
Recombinant (E.coli) Zaire Ebola virus nucleoprotein (EBOV NP) (full length, his-tag, 82 kda), purified
EVNP15-R-10
Alpha Diagnostics
10 ug
EUR 416.4
Recombinant (E.coli) Zaire Ebola virus nucleoprotein (EBOV NP) (full length, his-tag, 82 kda), purified
EVNP15-R-100
Alpha Diagnostics
100 ug
EUR 2617.2
Zaire ebolavirus Nucleoprotein (NP)
1-CSB-EP323576ZAB
Cusabio
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10ug 50ug 100ug 200ug 500ug 1MG
Description: Recombinant Zaire ebolavirus Nucleoprotein(NP) ,partial expressed in E.coli
Zaire ebolavirus Nucleoprotein (NP)
1-CSB-EP323576ZABa2
Cusabio
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10ug 50ug 100ug 200ug 500ug 1MG
Description: Recombinant Zaire ebolavirus Nucleoprotein(NP),partial expressed in E.coli
Zaire ebolavirus Nucleoprotein (NP)
1-CSB-YP323576ZAB
Cusabio
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10ug 50ug 100ug 200ug 500ug 1MG
Description: Recombinant Zaire ebolavirus Nucleoprotein(NP),partial expressed in Yeast
Ebola Zaire Nucleoprotein (Recombinant)
abx023563-1mg
Abbexa
1 mg
EUR 3224.4
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Antibody, Mouse MAb
MBS8110698-002mL
MyBiosource
0.02mL
EUR 185
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Antibody, Mouse MAb
MBS8110698-01mL
MyBiosource
0.1mL
EUR 365
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Antibody, Mouse MAb
MBS8110698-5x01mL
MyBiosource
5x0.1mL
EUR 1490
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Antibody, Mouse MAb
MBS8110699-002mL
MyBiosource
0.02mL
EUR 185
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Antibody, Mouse MAb
MBS8110699-01mL
MyBiosource
0.1mL
EUR 365
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Antibody, Mouse MAb
MBS8110699-5x01mL
MyBiosource
5x0.1mL
EUR 1490
Recombinant (E.coli) Zaire Ebola virus nucleoprotein (EBOV NP) (full length, his-tag, 82 kda)-Biotin Conjugate
EVNP15-BTN
Alpha Diagnostics
100 ul
EUR 489.6
Mouse Anti-Ebola Virus Nucleoprotein Antibody (Sudan/Zaire) (7G2)
MAB12168-100
The Native Antigen Company
0.1
EUR 307.91
Description: Mouse monoclonal antibody specific for Ebola virus nucleoprotein (Sudan/Zaire) (clone 7G2)
Human Anti-Zaire Ebola virus Nucleoprotein (NP) IgG ELISA Kit, 96 tests, Quantitative
AE-320520-1
Alpha Diagnostics
1 Kit
EUR 1074
Ebola Virus Nucleoprotein (NP) (Sudan)
REC31729-100
The Native Antigen Company
0.1
EUR 399.14
Description: Recombinant Ebolavirus NP (Sudan) C-term produced in E. coli.
Ebola Virus Nucleoprotein (NP) (Sudan)
REC31729-500
The Native Antigen Company
0.5
EUR 1399.58
Description: Recombinant Ebolavirus NP (Sudan) C-term produced in E. coli.
Rabbit Anti-Zaire Ebola virus Nucleoprotein (NP) IgG ELISA Kit, 96 tests, Quantitative
AE-320540-1
Alpha Diagnostics
1 kit
EUR 1074
Recombinant (E.coli) Zaire Ebola virus nucleoprotein (EBOV NP) (H.sapiens-wt/GIN/2014/Kissidougou-C15, 630-739aa, his-tag, >95%)
EVNP16-R-10
Alpha Diagnostics
10 ug
EUR 416.4
Recombinant (E.coli) Zaire Ebola virus nucleoprotein (EBOV NP) (H.sapiens-wt/GIN/2014/Kissidougou-C15, 630-739aa , his-tag, >95%)
EVNP16-R-100
Alpha Diagnostics
100 ug
EUR 2617.2
Ebola Virus Nucleoprotein (EBOV NP) Antibody
abx201313-100l
Abbexa
100 µl
EUR 450
Ebola Virus Nucleoprotein (EBOV NP) Antibody
abx201313-50l
Abbexa
50 µl
EUR 312.5
Ebola Virus Nucleoprotein (EBOV NP) Antibody
abx201314-100l
Abbexa
100 µl
EUR 450
Ebola Virus Nucleoprotein (EBOV NP) Antibody
abx201314-50l
Abbexa
50 µl
EUR 312.5
Ebola Virus Nucleoprotein (EBOV NP) Antibody
abx201315-100l
Abbexa
100 µl
EUR 450
Ebola Virus Nucleoprotein (EBOV NP) Antibody
abx201315-50l
Abbexa
50 µl
EUR 312.5
Ebola Virus Nucleoprotein (EBOV NP) Antibody
abx201316-100l
Abbexa
100 µl
EUR 450
Ebola Virus Nucleoprotein (EBOV NP) Antibody
abx201316-50l
Abbexa
50 µl
EUR 312.5
Ebola Virus Nucleoprotein (EBOV NP) Antibody
abx201317-100l
Abbexa
100 µl
EUR 450
Ebola Virus Nucleoprotein (EBOV NP) Antibody
abx201317-50l
Abbexa
50 µl
EUR 312.5
Ebola Virus Nucleoprotein (EBOV NP) Antibody
abx201320-100l
Abbexa
100 µl
EUR 325
Ebola Virus Nucleoprotein (EBOV NP) Antibody
abx201320-50l
Abbexa
50 µl
EUR 225
Ebola Virus Nucleoprotein (EBOV NP) Antibody
abx201325-100l
Abbexa
100 µl
EUR 450
Ebola Virus Nucleoprotein (EBOV NP) Antibody
abx201325-50l
Abbexa
50 µl
EUR 312.5
Ebola Virus Nucleoprotein (EBOV NP) Antibody
abx201326-100l
Abbexa
100 µl
EUR 450
Ebola Virus Nucleoprotein (EBOV NP) Antibody
abx201326-50l
Abbexa
50 µl
EUR 312.5
Ebola Virus Nucleoprotein (EBOV NP) Antibody
abx201327-100l
Abbexa
100 µl
EUR 450
Ebola Virus Nucleoprotein (EBOV NP) Antibody
abx201327-50l
Abbexa
50 µl
EUR 312.5
Monkey/Chimp Anti-Zaire Ebola virus Nucleoprotein (NP) IgG ELISA Kit, 96 tests, Quantitative
AE-320550-1
Alpha Diagnostics
1 kit
EUR 1074
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Antibody, Rabbit PAb
MBS8110700-002mL
MyBiosource
0.02mL
EUR 210
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Antibody, Rabbit PAb
MBS8110700-01mL
MyBiosource
0.1mL
EUR 320
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Antibody, Rabbit PAb
MBS8110700-5x01mL
MyBiosource
5x0.1mL
EUR 1300
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein / NP Protein (His Tag)
E45O54525E1-100
EnoGene
100 ug
EUR 1222.81
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Protein (His Tag)
MBS8122189-01mg
MyBiosource
0.1mg
EUR 450
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Protein (His Tag)
MBS8122189-5x01mg
MyBiosource
5x0.1mg
EUR 1885
Ebola virus Nucleoprotein Antibody, Mouse MAb
MBS8119515-002mL
MyBiosource
0.02mL
EUR 185
Ebola virus Nucleoprotein Antibody, Mouse MAb
MBS8119515-01mL
MyBiosource
0.1mL
EUR 365
Ebola virus Nucleoprotein Antibody, Mouse MAb
MBS8119515-5x01mL
MyBiosource
5x0.1mL
EUR 1490
Rabbit Anti-Zaire Ebola virus nucleoprotein (EBOV NP, 1-739/DNA vaccine) IgG
EVNP13-A
Alpha Diagnostics
100 ul
EUR 578.4
Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
CSB-EP323576ZAB
Cusabio
2867 mg
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Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
CSB-EP323576ZAB-20ug
Cusabio
20ug
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Description: 488-739aa
Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
CSB-EP323576ZABa2
Cusabio
2868 mg
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Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
CSB-EP323576ZABa2-20ug
Cusabio
20ug
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Description: 488-739aa
Recombinant Zaire ebolavirus Nucleoprotein(NP),partial
AP77628
SAB
1mg
EUR 2826
Recombinant Zaire ebolavirus Nucleoprotein(NP) ,partial
AP71016
SAB
1mg
EUR 2826
Recombinant Zaire ebolavirus Nucleoprotein(NP),partial
AP77241
SAB
each
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Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
CSB-YP323576ZAB
Cusabio
6205 mg
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Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
CSB-YP323576ZAB-20ug
Cusabio
20ug
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Description: 488-739aa
Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
MBS1206629-002mgBaculovirus
MyBiosource
0.02mg(Baculovirus)
EUR 1130
Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
MBS1206629-002mgEColi
MyBiosource
0.02mg(E-Coli)
EUR 375
Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
MBS1206629-002mgYeast
MyBiosource
0.02mg(Yeast)
EUR 420
Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
MBS1206629-01mgEColi
MyBiosource
0.1mg(E-Coli)
EUR 635
Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
MBS1206629-01mgYeast
MyBiosource
0.1mg(Yeast)
EUR 695
Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
MBS1001952-005mgBaculovirus
MyBiosource
0.05mg(Baculovirus)
EUR 1130
Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
MBS1001952-005mgMammalianCell
MyBiosource
0.05mg(Mammalian-Cell)
EUR 1385
Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
MBS1001952-05mgEColi
MyBiosource
0.5mg(E-Coli)
EUR 1130
Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
MBS1001952-05mgYeast
MyBiosource
0.5mg(Yeast)
EUR 1385
Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
MBS1001952-1mgEColi
MyBiosource
1mg(E-Coli)
EUR 1705
Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
MBS1485977-005mgBaculovirus
MyBiosource
0.05mg(Baculovirus)
EUR 1165
Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
MBS1485977-005mgEColi
MyBiosource
0.05mg(E-Coli)
EUR 920
Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
MBS1485977-005mgYeast
MyBiosource
0.05mg(Yeast)
EUR 1045
Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
MBS1485977-02mgEColi
MyBiosource
0.2mg(E-Coli)
EUR 1195
Recombinant Zaire ebolavirus Nucleoprotein (NP), partial
MBS1485977-05mgEColi
MyBiosource
0.5mg(E-Coli)
EUR 1315
Recombinant Zaire ebolavirus Nucleoprotein (NP) ,partial
RPC22461-100ug
Biomatik Corporation
100ug
EUR 635.8
Recombinant Zaire ebolavirus Nucleoprotein (NP) ,partial
RPC22461-1mg
Biomatik Corporation
1mg
EUR 2884.7
Recombinant Zaire ebolavirus Nucleoprotein (NP) ,partial
RPC22461-20ug
Biomatik Corporation
20ug
EUR 353.4
Recombinant Zaire ebolavirus Nucleoprotein (NP) ,partial
RPC22462-100ug
Biomatik Corporation
100ug
EUR 572
Recombinant Zaire ebolavirus Nucleoprotein (NP) ,partial
RPC22462-1mg
Biomatik Corporation
1mg
EUR 2884.7
Growth of coumarine derivatives as potent anti-filovirus entry inhibitors concentrating on viral glycoprotein Filoviruses, together with Ebolavirus (EBOV), Marburgvirus (MARV) and Cuevavirus, trigger hemorrhagic fevers in people with as much as 90% mortality charges. Within the 2014-2016 West Africa Ebola epidemic, there are 15,261 laboratory confirmed circumstances and 11,325 complete deaths.
The lack of efficient vaccines and medicines for the prevention and therapy of filovirus an infection in people stresses the urgency to develop antiviral therapeutics towards filovirus-associated ailments. Our earlier examine recognized a histamine receptor antagonist compound CP19 as an entry inhibitor towards each EBOV and MARV.
The preliminary structure-activity relationship (SAR) research of CP19 confirmed that its piperidine, coumarin and linker had been associated with its antiviral actions. On this examine, we carried out detailed SAR research on these teams with synthesized CP19 derivatives. We found that 1) the piperidine group could possibly be optimized with heterocycles, 2) the substitution teams of C3 and C4 of coumarin ought to be comparatively giant hydrophobic teams and three) the linker half ought to be least substituted.
Primarily based on the SAR evaluation, we synthesized compound 32 as a potent entry inhibitor of EBOV and MARV (IC50 = 0.5 μM for EBOV and 1.5 μM for MARV). The mutation research of Ebola glycoprotein and molecular docking research confirmed that the coumarin and its substituted teams of compound 32 bind to the pocket of Ebola glycoprotein in an analogous strategy to the revealed entry inhibitor compound 118a.
Nonetheless, the carboxamide group of compound 32 doesn’t have robust interplay with N61 as compound 118a does. The coumarin skeleton construction and the binding mannequin of compound 32 elucidated by this examine could possibly be utilized to information additional design and optimization of entry inhibitors concentrating on the filovirus glycoproteins.
Mouse anti Ebola Virus envelope glycoprotein GP (Zaire) (M921)
MAB12322-500
The Native Antigen Company
0.5
EUR 697.86
Description: Mouse monoclonal antibody specific for Ebola virus envelope glycoprotein GP (Zaire) (clone M921)
Mouse anti Ebola Virus envelope glycoprotein GP (Zaire) (M922)
MAB12323-100
The Native Antigen Company
0.1
EUR 278.11
Description: Mouse monoclonal antibody specific for Ebola virus envelope glycoprotein GP (Zaire) (clone M922).
Mouse anti Ebola Virus envelope glycoprotein GP (Zaire) (M922)
MAB12323-500
The Native Antigen Company
0.5
EUR 697.86
Description: Mouse monoclonal antibody specific for Ebola virus envelope glycoprotein GP (Zaire) (clone M922).
Zaire Ebola Virus Glycoprotein (EBOV GP antigen) ELISA Kit, 48 tests, Quantitative
AE-320800-48
Alpha Diagnostics
1 kit
EUR 1074
Zaire Ebola Virus Glycoprotein (EBOV GP antigen) ELISA Kit, 96 tests, Quantitative
AE-320800-96
Alpha Diagnostics
1 kit
EUR 1804.8
Ebola Virus Envelope Glycoprotein (GP) (Zaire, Kikwit-95)
EBOVKW95-ENV-100
The Native Antigen Company
0.1
EUR 677.26
Description: Recombinant Ebolavirus EBOV (subtype Zaire,strain Kikwit-95) Envelope Glycoprotein (GP) protein produced in HEK293 cells. Protein contains a C-terminal His-tag.
Ebola Virus Envelope Glycoprotein (GP) (Zaire, Kikwit-95)
EBOVKW95-ENV-1000
The Native Antigen Company
1
EUR 4317.2
Description: Recombinant Ebolavirus EBOV (subtype Zaire,strain Kikwit-95) Envelope Glycoprotein (GP) protein produced in HEK293 cells. Protein contains a C-terminal His-tag.
Ebola Virus Envelope Glycoprotein (GP) (Zaire, Kikwit-95)
EBOVKW95-ENV-250
The Native Antigen Company
0.25
EUR 1220.61
Description: Recombinant Ebolavirus EBOV (subtype Zaire,strain Kikwit-95) Envelope Glycoprotein (GP) protein produced in HEK293 cells. Protein contains a C-terminal His-tag.
Ebola Virus Envelope Glycoprotein (GP) (Zaire, Boende-Lokolia)
REC31740-100
The Native Antigen Company
0.1
EUR 457.08
Description: Recombinant Zaire ebola virus GP (NCBI AIO11753, AA1-637) was produced with a C-terminal His-tag. in HEK293 cells, and purified from culture supernatant by a series of immobilised metal affinity, ion exchange and size exclusion chromatography.
Ebola Virus Envelope Glycoprotein (GP) (Zaire, Boende-Lokolia)
REC31740-250
The Native Antigen Company
0.25
EUR 824.04
Description: Recombinant Zaire ebola virus GP (NCBI AIO11753, AA1-637) was produced with a C-terminal His-tag. in HEK293 cells, and purified from culture supernatant by a series of immobilised metal affinity, ion exchange and size exclusion chromatography.
Recombinant (HEK) Zaire Ebola virus glycoprotein/GP (Mayinga 1976, 1-647aa, >95%)
EVGP35-R-10
Alpha Diagnostics
10 ug
EUR 416.4
Monkey Anti-Reston Ebola virus glycoprotein (REBOV GP) IgG ELISA Kit, 96 tests, Quantitative
AE-323630-1
Alpha Diagnostics
1 Kit
EUR 1074
Mouse Anti-Zaire Ebola virus glycoprotein (GP) IgG ELISA Kit, 96 tests, Quantitative
AE-320600-1
Alpha Diagnostics
1 kit
EUR 1074
Human Anti-Zaire Ebola virus glycoprotein (GP) IgG ELISA Kit, 96 tests, Quantitative
AE-320620-1
Alpha Diagnostics
1 Kit
EUR 1074
Rabbit Anti-Zaire Ebola virus glycoprotein (GP) IgG ELISA Kit, 96 tests, Quantitative
AE-320640-1
Alpha Diagnostics
1 kit
EUR 1074
Human Anti-Zaire Ebola virus glycoprotein (GP) IgG ELISA Kit, 5x96 tests, Quantitative
AE-320620-5
Alpha Diagnostics
1 pk
EUR 4882.8
Ebola Virus Envelope Glycoprotein (GP1) (Zaire, Kikwit-95)
EBOVKW95-GP1-100
The Native Antigen Company
0.1
EUR 607.73
Description: Recombinant Ebolavirus EBOV (subtype Zaire,strain Kikwit-95) Envelope Glycoprotein 1 (GP1) protein produced in HEK293 cells. Protein contains a C-terminal His-tag.
Ebola Virus Envelope Glycoprotein (GP1) (Zaire, Kikwit-95)
EBOVKW95-GP1-1000
The Native Antigen Company
1
EUR 3884.58
Description: Recombinant Ebolavirus EBOV (subtype Zaire,strain Kikwit-95) Envelope Glycoprotein 1 (GP1) protein produced in HEK293 cells. Protein contains a C-terminal His-tag.
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) GP-RBD/Glycoprotein Protein
MBS8122166-01mg
MyBiosource
0.1mg
EUR 450
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) GP-RBD/Glycoprotein Protein
MBS8122166-5x01mg
MyBiosource
5x0.1mg
EUR 1885
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP Antibody, Mouse MAb
MBS8110663-002mL
MyBiosource
0.02mL
EUR 185
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP Antibody, Mouse MAb
MBS8110663-01mL
MyBiosource
0.1mL
EUR 365
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP Antibody, Mouse MAb
MBS8110663-5x01mL
MyBiosource
5x0.1mL
EUR 1490
Recombinant Zaire ebolavirus (strain Kikwit-95) (ZEBOV) (Zaire Ebola virus) Envelope glycoprotein
MBS1107736-002mgEColi
MyBiosource
0.02mg(E-Coli)
EUR 375
Recombinant Zaire ebolavirus (strain Kikwit-95) (ZEBOV) (Zaire Ebola virus) Envelope glycoprotein
MBS1107736-01mgEColi
MyBiosource
0.1mg(E-Coli)
EUR 635
Recombinant Zaire ebolavirus (strain Kikwit-95) (ZEBOV) (Zaire Ebola virus) Envelope glycoprotein
MBS1107736-1mgEColi
MyBiosource
1mg(E-Coli)
EUR 1925
Recombinant Zaire ebolavirus (strain Kikwit-95) (ZEBOV) (Zaire Ebola virus) Envelope glycoprotein
MBS1107736-5x1mgEColi
MyBiosource
5x1mg(E-Coli)
EUR 8405
Ebola Virus Envelope Glycoprotein (GP1) (Zaire, Boende-Lokolia)
REC31741-100
The Native Antigen Company
0.1
EUR 457.08
Description: Recombinant Zaire ebola virus GP1 (NCBI AIO11753, AA1-501) was produced with a C-terminal His-tag. in HEK293 cells, and purified from culture supernatant by a series of immobilised metal affinity, ion exchange and size exclusion chromatography.
Ebola Virus Envelope Glycoprotein (GP1) (Zaire, Boende-Lokolia)
REC31741-250
The Native Antigen Company
0.25
EUR 824.04
Description: Recombinant Zaire ebola virus GP1 (NCBI AIO11753, AA1-501) was produced with a C-terminal His-tag. in HEK293 cells, and purified from culture supernatant by a series of immobilised metal affinity, ion exchange and size exclusion chromatography.
Monkey/Chimp Anti-Zaire Ebola virus VP40 IgG ELISA Kit, 96 tests, Quantitative
AE-320750-1
Alpha Diagnostics
1 kit
EUR 1074
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein / GP Protein (His Tag)
E45O55443I2-100
EnoGene
100 ug
EUR 1222.81
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP Protein (His Tag)
MBS8122165-01mg
MyBiosource
0.1mg
EUR 450
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP Protein (His Tag)
MBS8122165-5x01mg
MyBiosource
5x0.1mg
EUR 1885
Mouse Monoclonal Anti-Anti-Zaire Ebola virus glycoprotein (EBOV GP) IgG, purified
EVGP20-M
Alpha Diagnostics
100 ul
EUR 578.4
Horse Anti-Zaire Ebola virus glycoprotein IgG ELISA Kit, 96 tests, Quantitative
AE-320690-1
Alpha Diagnostics
1 Kit
EUR 1220.4
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) GP-RBD/Glycoprotein Antibody, Rabbit PAb
MBS8110664-002mL
MyBiosource
0.02mL
EUR 210
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) GP-RBD/Glycoprotein Antibody, Rabbit PAb
MBS8110664-01mL
MyBiosource
0.1mL
EUR 320
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) GP-RBD/Glycoprotein Antibody, Rabbit PAb
MBS8110664-5x01mL
MyBiosource
5x0.1mL
EUR 1300
Zaire Ebola virus glycoprotein (EVGP) coated plate for use in #AE-320620 ELISA kit (5 plates/pk)
AE-320621
Alpha Diagnostics
1
EUR 2215.2
Monkey/Chimp Anti-Marburg (Angola) glycoprotein (GP) IgG ELISA Kit, 96 tests, Quantitative
AE-322650-1
Alpha Diagnostics
1 kit
EUR 1074
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) GP-RBD / Glycoprotein Protein (His Tag)
E45O55179M2-100
EnoGene
100 ug
EUR 1222.81
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) GP-RBD/Glycoprotein Protein (His Tag)
MBS8118776-01mg
MyBiosource
0.1mg
EUR 450
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) GP-RBD/Glycoprotein Protein (His Tag)
MBS8118776-5x01mg
MyBiosource
5x0.1mg
EUR 1885
Recombinant Zaire ebolavirus (strain Eckron-76) (ZEBOV) (Zaire Ebola virus) Pre-small/secreted glycoprotein
MBS1245951-002mgEColi
MyBiosource
0.02mg(E-Coli)
EUR 375
Recombinant Zaire ebolavirus (strain Eckron-76) (ZEBOV) (Zaire Ebola virus) Pre-small/secreted glycoprotein
MBS1245951-002mgYeast
MyBiosource
0.02mg(Yeast)
EUR 420
Recombinant Zaire ebolavirus (strain Eckron-76) (ZEBOV) (Zaire Ebola virus) Pre-small/secreted glycoprotein
MBS1245951-01mgEColi
MyBiosource
0.1mg(E-Coli)
EUR 635
Recombinant Zaire ebolavirus (strain Eckron-76) (ZEBOV) (Zaire Ebola virus) Pre-small/secreted glycoprotein
MBS1245951-01mgYeast
MyBiosource
0.1mg(Yeast)
EUR 695
Recombinant Zaire ebolavirus (strain Eckron-76) (ZEBOV) (Zaire Ebola virus) Pre-small/secreted glycoprotein
MBS1245951-05mgYeast
MyBiosource
0.5mg(Yeast)
EUR 1505
Monkey/Chimp Anti-Zaire Ebola virus Nucleoprotein (NP) IgG ELISA Kit, 96 tests, Quantitative
AE-320550-1
Alpha Diagnostics
1 kit
EUR 1074
Guinea pig Anti-Zaire Ebola virus glycoprotein IgG ELISA Kit, 96 tests, Quantitative
AE-320695-1
Alpha Diagnostics
1 Kit
EUR 1220.4
Recombinant (sf9) Zaire Ebola virus glycoprotein/GP (Mayinga 1976, 1-650aa, his-tag at CT, >95%), low endotoxin
EVGP31-R-10
Alpha Diagnostics
10 ug
EUR 416.4
Recombinant (sf9) Zaire Ebola virus glycoprotein/GP (Mayinga 1976, 1-650aa, his-tag at CT, >95%), low endotoxin
EVGP31-R-100
Alpha Diagnostics
100 ug
EUR 2617.2
Recombinant (sf9) Zaire Ebola virus glycoprotein/GP (Mayinga 1976, 1-650aa, his-tag at CT, >95%), low endotoxin
EVGP31-R-1000
Alpha Diagnostics
1000 ug
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Mouse Anti-Sudan Ebola virus glycoprotein (GP) IgG ELISA Kit, 96 tests, Quantitative
AE-321600-1
Alpha Diagnostics
1 kit
EUR 1074
Human Anti-Sudan Ebola virus glycoprotein (GP) IgG ELISA Kit, 96 tests, Quantitative
AE-321620-1
Alpha Diagnostics
1 Kit
EUR 1074
Mouse Anti-Zaire Ebola virus glycoprotein (GP) IgM ELISA Kit, 96 tests, Quantitative
AE-320610-1
Alpha Diagnostics
1 kit
EUR 1074
Human Anti-Zaire Ebola virus glycoprotein (GP) IgM ELISA Kit, 96 tests, Quantitative
AE-320630-1
Alpha Diagnostics
1 Kit
EUR 1074
Zaire Ebola virus Glycoprotein (GP), T cell epitope (577-584) (Thr-Glu-Leu-Arg-Thr-Phe-Ser-Ile) (MW: 966.1)
SP-89925-1
Alpha Diagnostics
1 mg
Ask for price
Recombinant Ebola Zaire Glycoprotein
MBS140853-01mg
MyBiosource
0.1mg
EUR 330
Recombinant Ebola Zaire Glycoprotein
MBS140853-05mg
MyBiosource
0.5mg
EUR 825
Recombinant Ebola Zaire Glycoprotein
MBS140853-1mg
MyBiosource
1mg
EUR 1515
Recombinant Ebola Zaire Glycoprotein
MBS140853-5x1mg
MyBiosource
5x1mg
EUR 6485
Ebola Zaire Glycoprotein Recombinant
rAP-5179
Angio Proteomie
Inquiry
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Human Anti-Zaire Ebola virus glycoprotein (GP) IgM ELISA Kit, 5x96 tests, Quantitative
AE-320630-5
Alpha Diagnostics
1 pk
EUR 4531.2
Biotin-Recombinant (sf9) Zaire Ebola virus glycoprotein/GP (Mayinga 1976, 1-650aa, his-tag at CT, >95%), low endotoxin
EVGP31-BTN
Alpha Diagnostics
10 ug
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Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP Antibody, Rabbit PAb, Antigen Affinity Purified
MBS8119503-002mL
MyBiosource
0.02mL
EUR 185
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP Antibody, Rabbit PAb, Antigen Affinity Purified
MBS8119503-01mL
MyBiosource
0.1mL
EUR 385
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP Antibody, Rabbit PAb, Antigen Affinity Purified
MBS8119503-5x01mL
MyBiosource
5x0.1mL
EUR 1590
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP Insect Cell Lysate (WB positive control)
MBS8115977-03mg
MyBiosource
0.3mg
EUR 280
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP Insect Cell Lysate (WB positive control)
MBS8115977-5x03mg
MyBiosource
5x0.3mg
EUR 1205
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein / GP (Virion spike glycoprotein) Protein (His Tag)
E45O55449M2-100
EnoGene
100 ug
EUR 1222.81
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP (Virion spike glycoprotein) Protein (His Tag)
MBS8122188-01mg
MyBiosource
0.1mg
EUR 450
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP (Virion spike glycoprotein) Protein (His Tag)
MBS8122188-5x01mg
MyBiosource
5x0.1mg
EUR 1885
Zaire ebolavirus Envelope glycoprotein (GP)
1-CSB-EP311249ZAT
Cusabio
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10ug 50ug 100ug 200ug 500ug 1MG
Description: Recombinant Zaire ebolavirus Envelope glycoprotein(GP),partial expressed in E.coli
Zaire ebolavirus Envelope glycoprotein (GP)
1-CSB-YP310843ZAA
Cusabio
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10ug 50ug 100ug 200ug 500ug 1MG
Description: Recombinant Zaire ebolavirus Envelope glycoprotein(GP),partial expressed in Yeast
Sudan Ebola Virus Glycoprotein (GP)
REC32011-100
The Native Antigen Company
0.1
EUR 452.9
Description: Recombinant Sudan ebola virus glycoprotein soluble domain (AA32-649) produced in HEK293 cells and purified from culture supernatant by immobilized metal affinity chromatography. The protein is cleaved by furin into GP1 and GP2 upon expression. This protein is predominantly monomeric
Sudan Ebola Virus Glycoprotein (GP)
REC32011-500
The Native Antigen Company
0.5
EUR 1924.78
Description: Recombinant Sudan ebola virus glycoprotein soluble domain (AA32-649) produced in HEK293 cells and purified from culture supernatant by immobilized metal affinity chromatography. The protein is cleaved by furin into GP1 and GP2 upon expression. This protein is predominantly monomeric
Monkey/Chimp Anti-VSV Indiana Glycoprotein (GP) antibody (VSVIG) IgG ELISA Kit, 96 tests, Quantitative
AE-327320-1
Alpha Diagnostics
1 Kit
EUR 1000.8
Rabbit Anti-Zaire Ebola virus glycoprotein (Mayinga/GP, 1-676aa/DNA vaccine) IgG, purified
EVGP15-A
Alpha Diagnostics
100 ul
EUR 578.4
Rabbit Anti-Zaire Ebola virus glycoprotein (Mayinga/GP 1-652aa/DNA vaccine) IgG, purified
EVGP16-A
Alpha Diagnostics
100 ul
EUR 578.4
Monkey/Chimp Anti-Zaire Ebola virus VP40 IgM ELISA Kit, 96 tests, Quantitative
AE-320760-1
Alpha Diagnostics
1 kit
EUR 1074
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP-RBD HEK293 Cell Lysate (WB positive control)
MBS8115976-03mg
MyBiosource
0.3mg
EUR 280
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP-RBD HEK293 Cell Lysate (WB positive control)
MBS8115976-5x03mg
MyBiosource
5x0.3mg
EUR 1205
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP-RBD (Receptor Binding Domain) Protein (Fc Tag)
MBS8122164-01mg
MyBiosource
0.1mg
EUR 450
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP-RBD (Receptor Binding Domain) Protein (Fc Tag)
MBS8122164-5x01mg
MyBiosource
5x0.1mg
EUR 1885
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP Antibody, Mouse MAb
MBS8110694-002mL
MyBiosource
0.02mL
EUR 185
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP Antibody, Mouse MAb
MBS8110694-01mL
MyBiosource
0.1mL
EUR 365
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP Antibody, Mouse MAb
MBS8110694-5x01mL
MyBiosource
5x0.1mL
EUR 1490
